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Chemoselective Nucleophilic Attack of .alpha.,.alpha.-Dicyano Epoxides: A Simple Synthesis of .alpha.-Amino Amides, Epoxy Amidines and Their Cyclic Analogs

✍ Scribed by Hurtaud, Dominique; Baudy-Floc'h, Michele; Robert, Albert; Le Grel, Philippe

Book ID: 126267996
Publisher: American Chemical Society
Year: 1994
Tongue: English
Weight: 333 KB
Volume: 59
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo00095a059

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ChemInform Abstract: A General and Simple Synthesis of α-Halo Amides via α,. alpha.-Dicyano Epoxides.

✍ M.-G. LE PIRONNEC; J.-L. GUINAMANT; A. ROBERT; M. BAUDY-FLOC'H 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

A General and Simple Synthesis of α-Halo Amides via α,. alpha.-Dicyano Epoxides. -A new convenient one-pot synthesis of the title compounds is presented with a view to their synthetic value as starting materials for the preparation of α-lactams, dioxopiperazines and oxazolidines. -(LE