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Chemoselective ligation techniques: Modern applications of time-honored chemistry

โœ Scribed by Theresa K. Tiefenbrunn; Philip E. Dawson

Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
810 KB
Volume
94
Category
Article
ISSN
0006-3525

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๐Ÿ“œ SIMILAR VOLUMES

Preparation and application of O-amino-s
Preparation and application of O-amino-serine, Ams, a new building block in chemoselective ligation chemistry
โœ Jane C. Spetzler; Thomas Hoeg-Jensen ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 131 KB

The non-codable amino acid O-amino-serine, Ams, has been prepared in both L-and D-forms as the orthogonally protected derivative, Fmoc-Ams(Boc)-OH (1 and 2). This new amino acid derivative is useful for chemoselective ligations. Under acidic conditions and in the presence of all other common amino a