Chemoselective and Regiospecific Synthesis of Iminospiro-γ-lactones from Maleic Anhydride or Citraconic Anhydride and Alkyl Isocyanides with Dialkyl Acetylenedicarboxylates

✍ Scribed by Mohammad Bayat; Hossien Imanieh; Hossien Abbasi

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: German
• Weight: 156 KB
• Volume: 93
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200900292

✦ Synopsis

Abstract

Isocyanides, dialkyl acetylenedicarboxylates (=dialkyl but‐2‐ynedioates), and anhydrides such as maleic anhydride (=furan‐2,3‐dione) or citraconic anhydride (=3‐methylfuran‐2,3‐dione) react in one pot to afford novel iminospiro‐γ‐lactones in fairly good yields at room temperature (Schemes 1 and 3).