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Chemorepulsion of Neuronal Migration by Slit2 in the Developing Mammalian Forebrain

✍ Scribed by Huaiyu Hu

Book ID
117608046
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
411 KB
Volume
23
Category
Article
ISSN
0896-6273

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Although cell migration is crucial for neural development, molecular mechanisms guiding neuronal migration have remained unclear. Here we report that the secreted protein Slit repels neuronal precursors migrating from the anterior subventricular zone in the telencephalon to the olfactory bulb. Our r