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Chemometric method to optimize chiral separation of imidazole derivatives by capillary electrophoresis

✍ Scribed by Yves Claude Guillaume; Eric Peyrin

Book ID
117225015
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
121 KB
Volume
50
Category
Article
ISSN
0039-9140

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Chiral selective separation of tocainide
Chiral selective separation of tocainide by capillary electrophoresis using various cyclodextrin derivatives
✍ ZoltΓ‘n Juvancz; Karin E. Markides; LΓ‘szlΓ³ Jicsinszky; RΓ³bert IvΓ‘nyi πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 102 KB

## Abstract Chiral separation of tocainide, an antiarrythmic agent, was solved using the capillary electrophoresis method. Fifteen types of cyclodextrins were tried as chiral selective buffer additives, and baseline separation was achieved with five of them. The variables that were studied comprise