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Chemometric Approach in Quantification of Structural Identity/Similarity of Proteins in Biopharmaceuticals.

✍ Scribed by S. Zuperl; P. Pristovsek; V. Menart; V. Gaberc-Porekar; M. Novic


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract Proteins present in two mitochondria preparations were separated by 2‐D chromatography using the ProteomeLab^TM^ PF‐2D Protein Fractional System, protein fractionation in two dimensions (PF‐2D). The proteins in each first‐dimension fraction were determined by trypsinization and LC‐MS/MS