Chemokines in the Inflammatory Bowel Diseases
โ Scribed by Richard P. MacDermott
- Book ID
- 110397246
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 686 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0271-9142
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๐ SIMILAR VOLUMES
Chemokines, a large family of small chemoattractive cytokines, and their receptors play an integral role in the regulation of the immune response and homeostasis. The ability of chemokines to attract specific populations of immune cells sets them apart from other chemoattractants. Chemokines produce
Two chemotactic cytokines, monocyte chemoattractant protein-1 (MCP-1) and RANTES, possibly contribute to the recruitment and activation of leukocytes in inflamed tissues. The expression of these cytokine genes was evaluated in tissue sections from resected bowel segments of 14 patients with inflamma