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Chemokines bind to sulfatides as revealed by surface plasmon resonance

✍ Scribed by Roger Sandhoff; Heike Grieshaber; Roghieh Djafarzadeh; Tjeerd P. Sijmonsma; Amanda E.I. Proudfoot; Tracy M. Handel; Herbert Wiegandt; Peter J. Nelson; Hermann-Josef Gröne

Book ID
116272873
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
738 KB
Volume
1687
Category
Article
ISSN
1388-1981

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## Abstract All IgGs are homobivalent, but their ability to bind bivalently to the surface of a virus particle depends mainly on a favourable spacing of cognate epitopes and the angle that the FAb arm makes with the virus surface. If the angle of binding forces the second FAb arm to point into solu