Chemokines as inflammatory mediators of fibrosis in liver fibrosis
โ Scribed by H E Wasmuth
- Book ID
- 120690414
- Publisher
- BioMed Central
- Year
- 2010
- Tongue
- English
- Weight
- 116 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1479-5876
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๐ SIMILAR VOLUMES
Hepatic fibrosis occurs during most chronic liver diseases and is driven by inflammatory responses to injured tissue. Because DCs are central to modulating liver immunity, we postulated that altered DC function contributes to immunologic changes in hepatic fibrosis and affects the pathologic inflamm
## Abstract ## Background The interaction between fibrogenic cells and extracellular matrix plays a role in liver fibrosis, yet the mechanisms are largely unknown. Secreted protein, acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that is expressed by hepatic stellate cells and