Chemokines and their receptors in rheumatoid arthritis: Future targets?
β Scribed by Alisa E. Koch
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 179 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Rheumatoid arthritis (RA) is a chronic inflammatory condition characterized by a cellular influx and destruction of the joint architecture. Chemokines characteristically regulate leukocyte recruitment and activation. Chemokine (CC motif) receptorβlike 2 (CCRL2) is an orpha
## Abstract ## Objective To explore the potential involvement of the chemokine system in synoviocyteβmediated tissue destruction in rheumatoid arthritis (RA), we studied the expression profile of chemokine receptors and their function in the migration, proliferation, and matrix metalloproteinase (