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Chemokines and chemokine receptors: Update on utility and challenges for the clinician

✍ Scribed by Roy, Ishan; Evans, Douglas B.; Dwinell, Michael B.


Book ID
122250618
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
387 KB
Volume
155
Category
Article
ISSN
0039-6060

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The chemokine/chemokine-receptor family:
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The chemokines are a large superfamily of chemotactic cytokines that are utilized to direct the trafficking and migration of leukocytes within the immune system. The chemokines mediate their activity through a large family of G-proteincoupled receptors, and thus are highly tractable as therapeutic t