Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning
✍ Scribed by Françoise Mennicken; Rich Maki; Errol B de Souza; Rémi Quirion
- Book ID
- 117341858
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 141 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0165-6147
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Neuroinflammation has been implicated recently in the pathogenesis of many neurodegenerative diseases. The cross-talk between neurons and non-neuronal cells seems to be a critical step in the progression of neurodegeneration and molecules that have a beneficial role may turn into harmful players. Th
## Abstract Chemokines play specific roles in directing the recruitment of leukocyte subsets into inflammatory foci within the central nervous system (CNS). The involvement of these cytokines as mediators of inflammation is widely accepted. Recently, it has become evident that cells of the CNS (ast