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Chemoenzymic synthesis of the GM3-oligosaccharide [NeuNAcα(2–3)Galβ(1–4)Glc] on a water-soluble polymer support

✍ Scribed by Alexandra Tuchinsky; Uri Zehavi


Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
164 KB
Volume
39
Category
Article
ISSN
1381-5148

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Synthesis of Protected Hexp-(1 → 4)-β-D-GlcpNAc-(1 → 2)-α-D-Manp-(1 → O)(CH2)7CH3 Sequences (Hex: β-D-Glc, 4-deoxy-4fluoro-β-D-Gal, or 4-deoxy-β-D-Gal) Using a Glc-GlcNPhth Donor, Eventually Fluorinated or Deoxygenated at the Oligosaccharide Level. -The title trisaccharide derivatives are prepared