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Chemoenzymatic Total Synthesis of the Antiproliferative Polyketide (+)-(R)-Aureothin

✍ Scribed by Martina Werneburg; Christian Hertweck


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
218 KB
Volume
9
Category
Article
ISSN
1439-4227

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✦ Synopsis


Aureothin (1) is a densely functionalized polyketide metabolite of Streptomyces thioluteus that efficiently stalls proliferation of various tumor cells. The unusual nitroaryl and tetrahydrofuryl-[a] M.


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ChemInform Abstract: Chemoenzymatic Tota
✍ Martina Werneburg; Christian Hertweck πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 25 KB

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