Chemoenzymatic synthesis of conformationally rigid glutamic acid analogues
β Scribed by F. Trigalo; D. Buisson; R. Azerad
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 287 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
All stereomers of cyclohexane and cyclopentane+erived analogues of glutamic acid have been synthesized from the corresponding 3-keto-cycloalkyl carboxylic acid esters by a ccanbination of microbial steps and standard chemical methods.
π SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The stereoselective synthesis of cyclic amino acids incorporating the core framework of aspartic acid and glutamic acids were accomplished from a common intermediate. Oxidative cleavage of an aza-bicyelio.dichlorocycldmtanone/pentanone with MeaCuLi/AcaO followed by ozonolysis furnished the amino aci
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract As a part of our study of the cancerβspecific protease PSMA (prostateβspecific membrane antigen) we present a stereoselective synthesis of conformationally constrained glutamate mimetics. Key intermediates are azabicycloalkenes which are synthesized via diastereoselective or enantiosele