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Chemoenzymatic Approaches to Glycoprotein Synthesis

✍ Scribed by Clay S. Bennett; Chi-Huey Wong


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract The current project describes the chemoenzymatic modification of bovine ribonuclease B (RNase B) to contain a single glycosylation site with a known glycan. A reactive disaccharide oxazoline derivative was synthesized and stereospecifically added to deglycosylated RNase B through endo‐β