To generate non-small cell lung cancer (NSCLC)-reactive lymphocytes, we transfected an HLA-A2-expressing human NSCLC line (1355) with the cDNA encoding the lymphocyte co-stimulatory molecule CD80. Following selection in G418, 1355.7 demonstrated stable cell-surface expression of CD80. Allogeneic mix
Chemo-radioresistance of Small Cell Lung Cancer Cell Lines Derived from Untreated Primary Tumors Obtained by Diagnostic Bronchofiberscopy
โ Scribed by Tanio, Yoshiro ;Watanabe, Masatoshi ;Inoue, Tamotsu ;Kawase, Ichiro ;Shirasaka, Takuma ;Ikeda, Toshiyuki ;Hara, Hideki ;Masuno, Tomiya ;Saito, Shin'ichi ;Kawano, Kiyoshi ;Kitamura, Hajime ;Kubota, Kaoru ;Kodama, Nagahisa ;Kawahara, Masaaki ;Sakatani, Mitsunori ;Furuse, Kiyoyuki ;Yamamoto, Satoru ;Kishimoto, Susumu
- Book ID
- 108579047
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1990
- Tongue
- English
- Weight
- 702 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0910-5050
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In a small-cell lung carcinoma (SCLC) tumor specimen as well as in 3 cell lines derived from SCLC biopsies obtained from the same patient at successive times during the clinical course, either the N-myc gene or the c-myc gene appeared to be amplified and expressed. The initial tumor specimen, a lymp