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Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds

✍ Scribed by Nakano, Toshiki; Yagi, Yusuke; Miyahara, Mizuki; Kaminura, Akio; Kawatsura, Motoi; Itoh, Toshiyuki


Book ID
120171213
Publisher
Molecular Diversity Preservation International
Year
2011
Tongue
English
Weight
255 KB
Volume
16
Category
Article
ISSN
1420-3049

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Chiral zinc homoenolate of methyl isobut
✍ Eiichi Nakamura; Kouichi Sekiya; Isao Kuwajima πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 266 KB

Chiral homoenolate of methyl isobutyrate prepared in a few steps from optically active methyl A-hydroxy isobutyrate reacts with carbon electrophiles to give chiral o(-methyl esters. Approaches to asymmetric synthesis employing "chiral building blocks" play important roles in the preparation of chir