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Chemo- and regioselective reductions of functionalized epoxides by Bu3SnH/Bu3SnI-phosphine oxide

โœ Scribed by Takayo Kawakami; Daisuke Tanizawa; Ikuya Shibata; Akio Baba


Book ID
103400807
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
228 KB
Volume
36
Category
Article
ISSN
0040-4039

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Facile chelation-controlled reductive op
โœ Bao-Zhong Zheng; Megumi Yamauchi; Hiroo Dei; Shin-ichi Kusaka; Katsuya Matsui; O ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 222 KB

A mild and ecient regioselective reductive opening of methoxybenzylidene acetals using a combination of Bu 3 SnH and MgBr 2 . OEt 2 , mainly via ยฎve-membered chelation intermediates is described. This reaction was applied to synthetic intermediates of myriaporon and tedanolide.