Chemo- and regioselective allylic oxidation: Oxo-derivatives of 2-phospholene sugar analogs

✍ Scribed by Valluru Krishna Reddy; Lakonda Nagaprasada Rao; Motoki Maeda; Buchammagari Haritha; Mitsuji Yamashita

• Book ID: 102231764
• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 104 KB
• Volume: 14
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.10154

✦ Synopsis

Abstract

A convenient and facile chemo‐ and regioselective oxidation of the allylic methylene group in a 2‐phospholene ring system afforded the novel carbonyl derivatives of 2‐phospholenes (2a–i). The method gives high conversion and selectivity in the formation of allylic ketones. The advantages of this oxidation method in such a five‐membered pseudo sugar 2‐phospholene ring are mentioned, and the oxidation is examined on several substituted 2‐phospholenes (1a–i). © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:320–325, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10154