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Chemistry of trifluoroacetic anhydride-haloacetic acid reactions with medroxyprogesterone

✍ Scribed by Samant, Bhaskar R.; Sweet, Frederick


Book ID
127392351
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
558 KB
Volume
42
Category
Article
ISSN
0022-3263

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Reaction of tryptophan with trifluoroace
✍ Jan Bergman; GΓΆran Lidgren πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 226 KB

Trifluoroacetic anhydride {TFAA) in ether quickly (= 5-10 min) converted tryptophau to the crystalline 2-trifluoromethyl-5(4@-oxazolone (2) without racemization. Dissolution of optically active 2 in acetonitrile gave racemic 2, whereas treatment with hot aqueous dioxane gave the isomeric oxazolone (