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Chemistry of antimony-based drugs in biological systems and studies of their mechanism of action

✍ Scribed by Frézard, Frédéric (author);Demicheli, Cynthia (author);Kato, Kelly C. (author);Reis, Priscila G. (author);Lizarazo-Jaimes, Edgar H. (author)


Book ID
125457329
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2013
Tongue
English
Weight
610 KB
Volume
33
Category
Article
ISSN
0193-4929

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Chemistry of antimony-based drugs in bio
✍ Frézard, Frédéric (author);Demicheli, Cynthia (author);Kato, Kelly C. (author);R 📂 Article 📅 2013 🏛 Walter de Gruyter GmbH & Co. KG 🌐 English ⚖ 610 KB

## Abstract Antimonial drugs have been used for a century in the therapy of the parasitic disease leishmaniasis. Even though pentavalent antimonials are still first-line drugs, they exhibit several limitations, including severe side effects, the need for daily parenteral administration and drug res