✦ LIBER ✦

Chemistry of aminophenols. Part 3: First synthesis of nitrobenzo[b]furans via a coupling–cyclization approach

✍ Scribed by Wei-Min Dai; Kwong Wah Lai

Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 186 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02333-x

No coin nor oath required. For personal study only.

✦ Synopsis

The first synthesis of 4-, 5-, and 6-nitrobenzo[b]furans has been achieved via the Sonogashira cross-coupling reaction of 2-iodonitrophenol acetates prepared from commercially available and inexpensive 2-aminonitrophenols. The obtained 2alkynylnitrophenol acetates were subjected to a KO t Bu-promoted cyclization at room temperature to form nitrobenzo[b]furans. Examples of the synthesis of other substituted benzo[b]furans and the one-pot coupling-cyclization are given.

📜 SIMILAR VOLUMES

Chemistry of Aminophenols. Part 3. First

Chemistry of Aminophenols. Part 3. First Synthesis of Nitrobenzo[b]furans via a Coupling—Cyclization Approach.

✍ Wei-Min Dai; Kwong Wah Lai 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 180 KB

## Abstract For Abstract see ChemInform Abstract in Full Text.

ChemInform Abstract: New Domino Approach

ChemInform Abstract: New Domino Approach for the Synthesis of 2,3-Disubstituted Benzo[b]furans via Copper-Catalyzed Multi Component Coupling Reactions Followed by Cyclization.

✍ Hongfeng Li; Jun Liu; Bin Yan; Yanzhong Li 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

ChemInform Abstract: Synthesis of 3-Alky

ChemInform Abstract: Synthesis of 3-Alkynyl-2-(methylsulfanyl)benzo[b]furans (III) via Sonogashira Cross-Coupling of 3-Iodo-2-(methylsulfanyl)benzo[b]furans (I) with Terminal Alkynes

✍ Flavia Manarin; Juliano A. Roehrs; Ricardo Brandao; Cristina W. Nogueira; Gilson 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

ChemInform Abstract: Intramolecular Cycl

ChemInform Abstract: Intramolecular Cyclization of O-(3,5-Dinitrophenyl) and O-(3-Amino-5-nitrophenyl) Ketoximes, Products of Transformations of 1,3,5-Trinitrobenzene. The Synthesis of Nitrobenzo[b]furans and 4-Hydroxynitroindoles.

✍ S. S. Vorob'ev; M. D. Dutov; I. A. Vatsadze; E. P. Petrosyan; V. V. Kachala; Yu. 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 43 KB

ChemInform Abstract: A Facile and Effici

ChemInform Abstract: A Facile and Efficient Synthesis of Thieno(2,3-c)furans and Furo(3,4-b) indoles via a Pummerer-Induced Cyclization Reaction.

✍ C. O. KAPPE; A. PADWA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 2 views

ChemInform Abstract: A New Approach to t

ChemInform Abstract: A New Approach to the Synthesis of Pyrido[4,3-b]indole Derivatives (γ-Carbolines) via Cyclization of Enamino Dinitriles.

✍ O. B. Smirnova; T. V. Golovko; L. M. Alekseeva; A. S. Shashkov; V. G. Granik 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 67 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v