✦ LIBER ✦
Chemische Verschiebungen bei 17O-NMR. und Hydratations geschwindigkeiten von cyclischen Ketonen mit transannularer Wechselwirkung
✍ Scribed by H. Dahn; H.-P. Schlunke; J. Temler
- Book ID
- 102855295
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- German
- Weight
- 642 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
In 8‐ and 9‐membered cyclic ketones, transannular interactions of an EtN group or an O atom shift considerably the ^17^O signal of the carbonyl group to higher fields; S appears to have no such effect. The same ketones show markedly diminished speeds of water addition, compared to simple ketones; this reaction was followed by measuring the rate of oxygen exchange between ^17^O‐labelled ketones and (unenriched) water. Transannular interaction inhibits completely in N‐ethyl‐azacyclodecane‐6‐one the exchange reaction, including labelling attemps.