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ChemInform Abstract: β-APP Processing as a Therapeutic Target for Alzheimer′s Disease

✍ Scribed by D. W. SMITH; B. MUNOZ

Publisher
John Wiley and Sons
Year
2010
Weight
27 KB
Volume
28
Category
Article
ISSN
0931-7597

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## Abstract One of the main neuropathological lesions observed in brain autopsy of Alzheimer's disease (AD) patients is the extracellular senile plaques mainly composed of amyloid‐beta (Aβ) peptide. Recently, treatment strategies have focused on modifying the formation, clearance, and accumulation