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ChemInform Abstract: α-Hydroxymethylphenylglycine and α- Hydroxymethylphenylalanine: Synthesis, Resolution, and Absolute Configuration.

✍ Scribed by A. OLMA


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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Optical resolution and absolute configur
✍ Masao Kawai; Keiichi Yamada; Kouji Hosoda; Yasuhiro Omori; Shuji Kato; Nobuhiro 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB

Optical resolution of racemic N-benzyloxycarbonyl-protected alpha-alkoxyglycines, (+/-)-Cbz-Gly(OR)-OH (R = Et and Pr(i)), was achieved by means of fractional crystallization of diastereomeric salts with (+)-(1S,2S)-2-amino-1-phenyl-1,3-propanediol or diastereomeric esters of (+)- or (-)-menthol. Th