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ChemInform Abstract: Vinylic C—F Bond Activation with Low-Valent Zirconocene: The Generation and Cross-Coupling Reactions of 1-Fluorovinylzirconocene.

✍ Scribed by Masaki Fujiwara; Junji Ichikawa; Tatsuo Okauchi; Toru Minami


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Vinylic C-F Bond Activation with Low-Valent Zirconocene: The Generation and Cross-Coupling Reactions of 1-Fluorovinylzirconocene. -Depending on the functional group Y, difluoroolefins (I) react with low valent Cp 2 Zr, generated in situ from Cp 2 ZrCl 2 and BuLi, to give a solution of either intermediate (E)-1-fluorovinylzirconocene or 2,2-difluorovinylzirconocene, the precursors of (III) or (IV), respectively. Reaction of the dimethylaminophenyl derivative (Id) with further aryl iodides results in formation of olefins (VI). -