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ChemInform Abstract: Use of the Ireland—Claisen Rearrangement in the Synthesis of 2,3-Disubstituted Succinates.

✍ Scribed by L. M. PRATT; S. A. BOWLES; S. F. COURTNEY; C. HIDDEN; C. N. LEWIS; F. M. MARTIN; R. S. TODD


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Enantiomeric Synthe
✍ J. H. HONG; K. LEE; Y. CHOI; C. K. CHU 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB

Enantiomeric Synthesis of 3'-Fluoro-Apionucleosides Using Claisen Rearrangement. -Starting from the triol (I), readily available from 1,2-O-isopropylidene-D-glyceraldehyde, an enantiomeric synthesis of 3'-fluoroapionucleosides such as (X) and (XI) is accomplished. The route to the key-intermediate