✦ LIBER ✦
ChemInform Abstract: Unusual Approach to 3-Aryl-2-aminopyridines Through a Radical Mechanism: Synthesis and Theoretical Rationale form Quantum Mechanical Calculations.
✍ Scribed by Marta Camacho-Artacho; Valentina Abet; Luis M. Frutos; Federico Gago; Julio Alvarez-Builla; Carolina Burgos
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 23 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
It is found that treatment of bromopyridines of type (I) with (Tms)~3~SiH and the nitrile ACN allows selective access to 3‐aryl‐2‐aminopyridines via radical ipso substitution.