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ChemInform Abstract: Trishomocubanes, a New Class of Selective and High Affinity Ligands for the Sigma Binding Site.

โœ Scribed by M. KASSIOU; V. H. NGUYEN; R. KNOTT; M. J. CHRISTIE; T. W. HAMBLEY


Book ID
112034623
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Trishomocubanes, a new class of selectiv
โœ Michael Kassiou; Vu H. Nguyen; Robert Knott; MacDonald J. Christie; Trevor W. Ha ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 279 KB

The synthesis, receptor binding, and preliminary structural characterisation of trishomocubanes of types pentacyclo [5.4.0.02'6.03'lยฐ.05'9]undecylamines and 4-azahexacyclo[5.4.1.0E'6.03'lยฐ.05'9.08'll]dodecanes are described. These ligands demonstrated high selectivity and affinity for the sigma bind