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ChemInform Abstract: Tricyclic Heteroaromatic Systems. 3-Substituted 1,2,3,5,6,7-Hexahydro- 2,5,6-trioxopyrazino(1,2,3-de)quinoxalines as Novel Antagonists at the Glycine-NMDA Site.

โœ Scribed by F. VARANO; D. CATARZI; V. COLOTTA; L. CECCHI; G. FILACCHIONI; A. GALLI; C. COSTAGLI


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel Renin Inhibit
โœ I. UCHIDA; ET AL. ET AL. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 34 KB

Novel Renin Inhibitors Containing (2S,3S,5S)-2-Amino-1-cyclohexyl-6-methyl-3,5-heptanediol Fragment as a Transition-State Mimic at the P1-P1' Cleavage Site. -A large variety of title compounds (18 examples) are prepared following the sequence shown for (VIa). All compounds containing the 2-amino-3,