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ChemInform Abstract: Total Synthesis of the Immunosuppressant (-)-Pironetin (PA48153C).

โœ Scribed by Gary E. Keck; Chad E. Knutson; Sarah A. Wiles

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Total Synthesis of
ChemInform Abstract: Total Synthesis of (-)-PA-48153C (Pironetin) Utilizing L-Quebrachitol as a Chiral Building Block.
โœ N. CHIDA; M. YOSHINAGA; T. TOBE; S. OGAWA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 37 KB

Total Synthesis of (-)-PA-48153C (Pironetin) Utilizing L-Quebrachitol as a Chiral Building Block. -An alternative approach to the novel immunosuppressant (XIV) is developed. The acyclic part (XI), containing four contiguous chiral centers, is constructed stereoselectively from L-quebrachitol (I). T