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ChemInform Abstract: Total Synthesis of the Epidermal Growth Factor Inhibitor (-)-Reveromycin B.

✍ Scribed by Anthony N. Cuzzupe; Craig A. Hutton; Michael J. Lilly; Robert K. Mann; Kenneth J. McRae; Steven C. Zammit; Mark A. Rizzacasa

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 32
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200134229

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## Synthesis of Modified Tripeptides and Tetrapeptides as Potential Bisubstrate Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase. -Compound (Ia) is the best bisubstrate-type inhibitor among the three peptides synthesized.