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ChemInform Abstract: Total Synthesis of Nucleobase-Modified Adenophostin A Mimics.

✍ Scribed by Satoshi Shuto; Graeme Horne; Rachel D. Marwood; Barry V. L. Potter


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
33
Category
Article
ISSN
0931-7597

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Total Synthesis of Nucleobase-Modified A
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The adenophostins exhibit approximately 10 Β± 100 times higher receptor binding and Ca 2 mobilising potencies in comparison with the natural second messenger d-myo-inositol 1,4,5trisphosphate [Ins(1,4,5)P 3 ]. Despite many synthetic attempts to determine the minimal structural requirement for this un

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v