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ChemInform Abstract: Total Synthesis of Natural PI-091, a New Platelet Aggregation Inhibitor of Microbial Origin.

โœ Scribed by R. SHIRAKI; A. SUMINO; K. TADANO; S. OGAWA

Book ID
112036442
Publisher
John Wiley and Sons
Year
2010
Weight
39 KB
Volume
27
Category
Article
ISSN
0931-7597

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Total synthesis of PI-201, a new platele
Total synthesis of PI-201, a new platelet aggregation inhibitor : Establishment of its absolute stereochemistry
โœ Kin-ichi Tadano; Takeshi Murata; Toshihito Kumagai; Seiichiro Ogawa ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 273 KB

Inuamolecular DiebAlder cyckmddition of enantiomerically enriched triene 16 could be attained under thermal conditions resulting in the formation of octahydronaphthalene derivatives 17-20, one of which was convexted into PI-201 (1) , a new platelet aggregation inHibitor. Quite recently, Hanada et al