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ChemInform Abstract: Total Synthesis of Galtamycinone, the Common Aglycon of the C-Glycosyl Naphthacenequinone Antibiotics.

✍ Scribed by T. MATSUMOTO; H. YAMAGUCHI; K. SUZUKI


Book ID
112037085
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
27
Category
Article
ISSN
0931-7597

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A benzo[a]naphthacenequinone core, an amino acid, and a disaccharide are the constituents of pradimicin-benanomicin antibiotics 1 (R =disaccharide), a class of natural products with significant antifungal and anti-HIV activities. The first total synthesis of pradimicinone (benanomicinone, 1; R =H),