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ChemInform Abstract: Total Synthesis of Dolatrienoic Acid: A Subunit of Dolastatin 14.

✍ Scribed by S. MOUNE; G. NIEL; M. BUSQUET; I. EGGLESTON; P. JOUIN

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis

1997 hydroxycarboxylic acids hydroxycarboxylic acids (ether carboxylic acids) (acyclic compounds) and esters P 0280 38 -103 Total Synthesis of Dolatrienoic Acid: A Subunit of Dolastatin 14. -Two diastereomers of the title compound, e.g. (IX) are prepared as key intermediates for the total synthesis of dolastatin 14 which shows high antiproliferative activity against human tumor cells. -(MOUNE, S.; NIEL,

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