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ChemInform Abstract: Total Syntheses of Macrocyclic Marine Alkaloids, Haliclamines A and B: A Convenient and Expeditious Assembly of 3-Sustituted Pyridine Derivatives with Different Alkyl Chains to the Bispyridinium Macrocycle.

✍ Scribed by Y. MORIMOTO; C. YOKOE; H. KURIHARA; T. KINOSHITA


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Total Syntheses of Macrocyclic Marine Alkaloids, Haliclamines A and B: A Convenient and Expeditious Assembly of 3-Sustituted Pyridine Derivatives with Different Alkyl Chains to the Bispyridinium Macrocycle.

-The key steps in the synthesis of the title compounds (VIII) and (IX) are coupling of the N-oxide (V) with the pyridines (VI) and cyclization of the resulting products.