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ChemInform Abstract: Three-Component Solvent-Free Synthesis of Highly Substituted Bicyclic Pyridines Containing a Ring-Junction Nitrogen.

✍ Scribed by Shengjiao Yan; Yulan Chen; Lin Liu; Nengqin He; Jun Lin

Publisher
John Wiley and Sons
Year
2011
Weight
44 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Three-Component Solvent-Free Synthesis of Highly Substituted Bicyclic Pyridines Containing a Ring-Junction Nitrogen. -A series of bicyclic pyridines (IV), (VI), (VIII), and (X) is readily prepared by a three component reaction of heterocyclic ketene aminals such as (I) and (IX) with active methylene compounds and triethyl orthoformate under solvent-free conditions. -(

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