ChemInform Abstract: The Synthesis of a Sulfone Containing Analogue of the Esperamicin-A1 Aglycone: A Hetero Diels—Alder Approach.
✍ Scribed by Jaya Prabhakaran; Herve Lhermitte; Jagattaran Das; T. K. Sasi-Kumar; David S. Grierson
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 36 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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## Synthesis of a Hybrid Analogue of the Esperamicin and Dynemicin Cores. -The compound (VI) represents an enediyne analogue hybrid of the core structures of esperamicin and dynemicin. Key step in the sequence is the intramolecular Reissert-type reaction of the anion of the Z-1,3-diyn-2-ene (III)