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ChemInform Abstract: The Structures of Premithramycinone and Demethylpremithramycinone, Plausible Early Intermediates of the Aureolic Acid Group Antibiotic Mithramycin.

✍ Scribed by J. ROHR; ET AL. ET AL.


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


The Structures of Premithramycinone and Demethylpremithramycinone, Plausible Early Intermediates of the Aureolic Acid Group Antibiotic Mithramycin.

-The structures of title compounds (I), determined in particular by one-and two-dimensional NMR spectroscopy, suggest that aureolic acid antibiotics are biosynthetically formed via a tetracycline-type, folded decaketide. -(ROHR,


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