The N-7 regioisomer of 2-chloro-2′-deoxy
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Victoria L. Worthington; William Fraser; Carl H. Schwalbe
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Article
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1995
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Elsevier Science
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English
⚖ 506 KB
The nucleoside 6-amino-2-chloro-7-(2-deoxy-fl-o-erythro-pentofuranosyl)-7H-purine 7 is readily accessible in two steps from 2,6-dichloropurine. The crystal structure of this unusual nucleoside reveals a bifurcated intramolecular hydrogen bond from the amino group to the O-5' with a weaker branch to