✦ LIBER ✦
ChemInform Abstract: The First Effective Syntheses of Cyanofluoromethylated Amides, Thioamides, and Phosphorus Compounds Using 2-Cyano-2-fluoro-2-phenylacetonitrile and Et3GeNa.
✍ Scribed by Yasuo Yokoyama; Kunio Mochida
- Book ID
- 101884997
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 36 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
The First Effective Syntheses of Cyanofluoromethylated Amides, Thioamides, and Phosphorus Compounds Using 2-Cyano-2-fluoro-2phenylacetonitrile and Et 3 GeNa.
-Various carbamoyl chlorides and chlorinated phosphorus compounds are cyanofluoromethylated by treatment with acetonitrile derivative (I) under promotion of NaGeEt 3 to give the title products. The syntheses of the phosphorus compounds are carried out at optimized reaction temperatures for each starting chloride. -(YOKOYAMA,