Stereochemical Issues Related to the Synthesis of 7,10- 10,16,3':3,4]pyrazino[1,2-b]βcarboline-5,8-diones. -The condensation of iminoethers like (III) with anthranilic acid proceeds with inversion of the tryptophan stereocenter C-16a. Epimerization of the tryptophan center also occurs by acylation
ChemInform Abstract: The Fate of the Tryptophan Stereocenter in the Synthesis of 7,10,16,16a-Tetrahydro-11H-quinazolino[2′,3′:3,4]pyrazino [1,2-b]β-carboline-5,8-diones.
✍ Scribed by Antonio Madrigal; Mercedes Grande; Carmen Avendano
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 38 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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