The enantioselective synthesis and antii
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Gregory Merriman; John J. Tegeler; R.Richard L. Hamer; Barbara S. Rauckman; Bria
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Article
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1995
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Elsevier Science
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English
โ 273 KB
Recently we identified three promising topically active antiinflammatory agents (2, 3, and 4) from a series of racemic aryl-sphingolipids that inhibit protein kinase C (PKC). We now wish to report the enantioselective synthesis of the aforementioned leads and their comparative biological profile. Th