The effect of various Lewis acids on the samarium diiodide other aromatic and aliphatic aldehydes syn-stereoselectivity was generally observed. Chiral Ξ±-alkylaldehydes allowed for promoted pinacol homocoupling of aldehydes was investigated. The reaction of benzaldehyde proceeded with an almost compl
ChemInform Abstract: The Effect of Lewis Acids on the Pinacol Homocoupling Reaction of Aldehydes Promoted by Samarium Diiodide.
β Scribed by Rita Annunziata; Maurizio Benaglia; Mauro Cinquini; Laura Raimondi
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 39 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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The samarium diiodide pinacol coupling of benzaldehyde diastereoselectivities of up to 7:1, while with cyclohexanecarboxaldehyde a stereoselectivity of up to 10:1 was and cyclohexanecarboxaldehyde in the presence of a variety of polyethylene glycols, including derivatives containing observed but in
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