## Abstract The degradation of cefaclor (1), an oral cephalosporin antibiotic, was studied at 37° in a neutral aqueous medium by HPLC and ^1^H‐NMR. Under these conditions, 1 underwent intramolecular aminolysis by the 7‐side‐chain NH~2~ group on the β‐lactam moiety to give a piperazine‐2,5‐dione. Th
ChemInform Abstract: The Degradation Mechanism of an Oral Cephalosporin: Cefaclor.
✍ Scribed by B. VILANOVA; J. DONOSO; F. MUNOZ; F. GARCIA-BLANCO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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