The astonishingly simple chiral ligand 1 was used in the first asymmetric variant of the Horner-Wadsworth-Emmons reaction. The products of olefination of 4-substituted cyclohexanones with lithium phosphanates arise via the resulting hydroxyphosphonates, which are present in high enantiomeric excess
✦ LIBER ✦
ChemInform Abstract: The Asymmetric Horner—Wadsworth—Emmons Reaction Mediated by an External Chiral Ligand.
✍ Scribed by M. MIZUNO; K. FUJII; K. TOMIOKA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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