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ChemInform Abstract: The Alkylation of Isatin-Derived Oximes: Spectroscopic and X-Ray Cystallographic Structural Characterization of Oxime and Nitrone Products.

✍ Scribed by Ny Sin; Brian L. Venables; Xiaohong Liu; Stella Huang; Qi Gao; Alicia Ng; Richard Dalterio; Ramkumar Rajamani; Nicholas A. Meanwell

Publisher
John Wiley and Sons
Year
2009
Weight
34 KB
Volume
40
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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The alkylation of isatin-derived oximes:
The alkylation of isatin-derived oximes: Spectroscopic and X-ray crystallographic structural characterization of oxime and nitrone products
✍ Ny Sin; Brian L. Venables; Xiaohong Liu; Stella Huang; Qi Gao; Alicia Ng; Richar 📂 Article 📅 2009 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 174 KB

## Abstract magnified image A series of isatin oximes was alkylated with alkyl halides and under Mitsunobu conditions to generate __O__‐alkylated oxime ether and __N__‐alkylated nitrone products. Alkylation of the sodium salts of oximes **5a** and **5b** with alkyl iodides produced predominantly t