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ChemInform Abstract: The 4-Anilinoquinazoline Class of Inhibitors of the erbB Family of Receptor Tyrosine Kinases

✍ Scribed by William A. Denny


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.


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Cancer chemoprevention trials can be directed at targeting established molecular mechanisms which contribute to neoplasia. One potential target is the ErbB/HER family of growth factor receptors with intrinsic tyrosine kinase activity. This group of four receptors mediates the action of multiple stro